Pune's Leading Immunotherapy Specialists — Advanced Care for Recurrent Implantation Failure & Miscarriage, with Proven Success Rates.
Immunotherapy in fertility care is a specialised treatment approach used when the body's own immune system may be interfering with successful conception or a healthy pregnancy. In some cases, immune-related factors can prevent an embryo from implanting properly or lead to repeated miscarriages, even when the embryo itself is healthy. Immunotherapy works by identifying and addressing these underlying immune imbalances, helping create a more favourable environment for implantation and pregnancy to progress. It's often recommended after recurrent implantation failure or recurrent pregnancy loss, once other possible causes have been ruled out through detailed evaluation. It's typically considered when standard fertility treatments haven't resulted in a successful pregnancy despite good-quality embryos, and immune-related factors are suspected to be playing a role. Recommended for recurrent implantation failure (RIF) Helpful for unexplained recurrent pregnancy loss An option after multiple unsuccessful IVF/embryo transfer cycles Suitable when immune-related markers are identified on testing Every immunotherapy plan is personal — your doctor will recommend the right protocol based on your diagnosis, test results, and fertility history.
It's one of the most effective and widely used fertility treatments today, often recommended when other, simpler options haven't worked or aren't suitable for your specific diagnosis.
Every IVF journey is personal — your doctor will recommend the right protocol based on your diagnosis, age, and individual fertility history.
Immunotherapy may be recommended when immune-related factors are suspected to be affecting implantation or pregnancy outcomes. Here are some situations when seeking specialist evaluation may be the right next step.
Repeated failed embryo transfers despite good-quality embryos may point to an immune-related cause. Testing can help identify the issue and guide the right treatment. Treatment can help identify the cause and explore suitable fertility options.
Multiple unexplained miscarriages may sometimes be linked to immune factors. Evaluation can help determine if immunotherapy is a suitable option.
Higher-than-normal natural killer (NK) cell levels can affect embryo implantation. Your specialist can recommend treatment based on your test results.
Existing autoimmune disorders can sometimes impact fertility and pregnancy outcomes. Coordinated care can help manage these concerns alongside fertility treatment.
This condition can increase the risk of implantation failure and miscarriage. Appropriate treatment may help improve pregnancy outcomes.
Sometimes, fertility problems occur even when routine tests do not identify a clear cause. A specialist can recommend additional immune evaluation and personalised treatment.
If previous IVF attempts have not resulted in pregnancy, further evaluation may be needed. Your doctor can review your results and suggest alternative treatment options.
When partners carry closely matching HLA markers, the mother's immune system may not generate the protective response a pregnancy normally needs — immunotherapy helps trigger that response artificially..
From your initial consultation to personalised care, discover what the Immunotherapy Treatment journey can look like, step by step..
Discuss your fertility history, previous cycles, and concerns with a specialist. This helps determine the next steps for a personalised treatment plan.
A comprehensive assessment to identify possible immune-related factors. Your doctor may recommend relevant tests based on your medical history.
A detailed evaluation may help assess specific immune-related factors that could be relevant to your fertility journey. Based on the findings, your fertility specialist can determine whether further evaluation or treatment may be appropriate.
Additional investigations to rule out other contributing causes. These results help your specialist understand the cause of infertility.
Your fertility specialist reviews your medical and fertility history along with relevant test results to identify factors that may be contributing to implantation or pregnancy-related concerns. This helps guide a personalised treatment approach.
Based on your medical history, test results, and individual fertility needs, your specialist develops a tailored treatment plan. This approach helps ensure that the recommended care is suited to your specific situation.
Based on your clinical assessment, your fertility specialist may recommend an appropriate immune-modulating approach as part of your treatment plan. The therapy is personalised according to your individual needs and treatment goals. .
Immunotherapy may be considered alongside an IVF or FET cycle as part of an individualized treatment plan. The approach is tailored based on your fertility history and clinical assessment, with the aim of supporting your overall reproductive care.
Regular follow-ups help your fertility specialist monitor your response to treatment and assess your progress. Based on your clinical evaluation, the treatment plan can be adjusted and the next steps guided accordingly.
A detailed immunological evaluation helps identify immune-related factors that may be associated with implantation or pregnancy concerns. This allows your specialist to better understand your individual fertility needs.
Your treatment plan is developed based on your medical history, test results, fertility journey, and specific clinical needs. This ensures that your care is tailored to your individual situation.
When clinically appropriate, immunotherapy may be considered as part of a personalised fertility treatment plan. It is designed to address specific immune-related factors that may be affecting reproductive outcomes.
For selected patients, immune-related evaluation may help identify factors that require further assessment. Your specialist can then guide appropriate treatment and ongoing pregnancy care.
Relevant immunological tests can provide additional information about specific immune-related factors. These findings can help your fertility specialist make informed treatment decisions.
From initial evaluation to follow-up, your fertility specialist monitors your progress and guides you through each stage. Regular consultations help ensure that your treatment plan remains appropriate for your needs.
Take a look around our clinic, labs, and patient care spaces.
























Real stories from real families who found success with us.
EXCELLENT Based on 159 reviews Posted on Google Tanaya Ajit PawarTrustindex verifies that the original source of the review is Google. Extremely happy with the services received here...specially thankful for the empathetic and compassionate care by Dr Samidha and the entire team here! They are available throughout the entire journey nd in every emergency..Kudos to the entire team for the quality care u all are providing!Posted on Google Santosh VitekariTrustindex verifies that the original source of the review is Google. Pune IVF Center - Best ConsultationPosted on Google Pankaj SuryavanshiTrustindex verifies that the original source of the review is Google. We are very delighted to share our happy moments.we have been taking treatment from various IVF centres in Pune without any success The day we visited Pune IVF at pimple saydagar we knew this place is different and has a positive vibe all around, right from the reception desk to the nursing staff all are very cooperative. Spacial thanks to Samidha madam for making our impossible journey a cakewalk for us. Thanks for being with us in our most difficult times . Our little bundle of joy is ready to conquer the world!Posted on Google 98as24Trustindex verifies that the original source of the review is Google. Very professional IVF clinic with good patient support. The staff is really helpful especially Arti sister. Dr Samidha explains the treatment options clearly and she is very empathetic towards patient. The package here also is very less and invlusive of all the medicines and charges. It is situated on the main BRT road as easily accessible from areas like sanghvi and pimple gurav.Posted on Google BIRU MOJUMDERTrustindex verifies that the original source of the review is Google. We had a positive experience during our fertility consultation here. The doctor is knowledgeable and the staff is very cooperative. For patients living in Sangvi, pimple gurav , the clinic location is convenient for regular visits.Posted on Google Pragati BalbudheTrustindex verifies that the original source of the review is Google. The staff is polite and the clinic environment is clean and professional. The doctor explains everything clearly and answers questions patiently. For couples from bhosari this is a good option for fertility consultation in Pune.Posted on Google Priti KambleTrustindex verifies that the original source of the review is Google. Very supportive doctor and well organised clinic.we felt comfortable discussing fertility concerns and the team guided us properly. This centre is convinient to visit from bhosari as it is on the main BRT road connecting wakad and bhosari.Posted on Google Dhruvin SuchakTrustindex verifies that the original source of the review is Google. good fertility clinic with experienced doctors and helpful staff.the entire process was explained step by step which made us feel comfortable . couples living in wakad can easily visit this centre for IVF consultation in pune .Posted on Google dipali RathodTrustindex verifies that the original source of the review is Google. We visited this IVF centre for consultation and were very satisfied with the experience. The doctor listens patiently and guides couples in a practical way. For people staying in Wakad, the clinic location is quite convenient and easy to reach.Posted on Google Shubhada GuptaTrustindex verifies that the original source of the review is Google. Very nice hospital, supportive staff, Mrs dalvi ma'am is too good, because all of you now I am also part of success stories. Thank you so much ma'am and staff too. 😊
Hear it from Dr. Samidha herself — real explainers on fertility and IVF treatment.
IVF Procedure Explained (Hindi)
Immunotherapy is a specialised approach used when immune-related factors may be preventing embryo implantation or causing recurrent pregnancy loss. It works by addressing immune imbalances to help create a more favourable environment for conception.
It's usually recommended for women who've had recurrent implantation failure, unexplained recurrent miscarriages, or multiple unsuccessful IVF cycles despite good-quality embryos, once other causes have been ruled out.
Diagnosis typically involves blood tests to check NK cell activity, antiphospholipid antibodies, thyroid antibodies, and other immune markers, along with a review of your reproductive and medical history.
Yes, when administered under specialist supervision. Your doctor will choose the appropriate therapy and dosage based on your test results and monitor you closely throughout the process.
Success varies based on the underlying immune factor, age, and embryo quality, but many patients see improved implantation rates once the immune barrier is addressed. Pune IVF has maintained a 76%+ overall success rate.
In cases where an immune cause is identified — such as elevated NK cells or antiphospholipid syndrome — immunotherapy can help reduce the risk of further pregnancy loss when combined with appropriate monitoring.
Cost depends on the type and duration of therapy required, along with any associated testing. Pune IVF explains all costs upfront with no hidden charges, and offers zero-cost EMI options.
Duration varies by individual case — some protocols are completed before an embryo transfer, while others continue through early pregnancy. Your specialist will outline a timeline based on your diagnosis.
Not always. Good-quality embryos can still fail to implant due to immune factors unrelated to embryo health. Testing helps determine if immunotherapy is actually needed in your case.
Yes, it's often integrated alongside an IVF or frozen embryo transfer (FET) cycle to support implantation, based on your doctor's assessment and treatment timeline.
Share a few details and our team will call you back to guide you through the next step.
Your details