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IVF का Success rate क्या होता है ? | IVF Success Rate in Hindi

– Published on 04 March 2024  

What are the Factors that Affect IVF Success Rate?

In vitro fertilization (IVF) is one of the greatest hopes for many couples who are struggling  with infertility. This medical procedure has evolved over the years and offers a chance to experience the joy of parenthood.

But its very important to note that not every IVF procedure succeeds in one attempt. There are numerous factors that affect the success of IVF.  So it’s important for couples to understand these elements to set realistic expectations and make informed decisions.

In this blog, we will take a look into these factors. So let’s get started.

IVF Success Rate Factors

Absolutely, let’s delve a bit deeper into the aspect of female age factors in IVF success:

Female Age Factors

The age of a woman is a significant factor in determining the success of IVF treatments. Here’s a breakdown of why this is the case:

  • Egg Quality and Quantity: As women age, both the quality and quantity of their eggs generally decrease. This natural decline starts to become more significant around the age of 35.
  • Age Under 35: Women in their 20s and early 30s usually have the highest quality and the largest number of eggs available. This is why they typically have higher IVF success rates.
  • The Mid-30s Shift: Around the mid-30s, changes start occurring. The eggs’ quality begins to drop, and there are fewer of them. This decrease in egg quality and quantity can lead to a lower chance of successful pregnancy through IVF.
  • 40s and Beyond: By the time a woman reaches her 40s, the chances of IVF success are lower, though not impossible. The decline in egg quality and quantity is more pronounced, increasing the risk of miscarriage and chromosomal abnormalities in the embryo.

It’s important to remember that age is not the only factor. Fertility varies greatly among individuals. Some women in their late 30s and 40s can have successful IVF treatments, especially with advancements in fertility technology.

For women over 35, especially those nearing 40, options like using donor eggs can be considered. This can significantly increase the chances of a successful pregnancy.

Male Age Factors

While it’s common to focus on female age in fertility discussions, the age of the male partner is also a key factor. Here’s a closer look:

  • Sperm Quality Decreases With Age: Men produce sperm throughout their lives. However, as they age, particularly past the age of 40, the quality of sperm can decline. This means the sperm may have more DNA fragmentation or chromosomal abnormalities.
  • Impact on Motility and Volume: Older men often experience a decrease in sperm motility (the sperm’s ability to move efficiently) and volume (the amount of sperm). These factors can reduce the likelihood of the sperm successfully fertilizing an egg.

 

The effect of male age on fertility is more subtle compared to female age. Nevertheless, it is significant, especially in IVF scenarios where every aspect of the sperm and egg quality matters.

For couples where the male partner is older, a thorough assessment of sperm quality can be helpful. This might include advanced semen analysis and possibly DNA fragmentation testing.

Uterine Causes

The health of the uterus plays a crucial role in the success of IVF. Here’s why:

  • Ideal Environment for Embryo: For a successful pregnancy, the uterus must provide a nurturing environment for the embryo to implant and grow. Any issues with the uterus can disrupt this process.
  • Common Uterine Issues:
  • Fibroids: These are noncancerous growths in or on the uterus. Depending on their size and location, they can interfere with implantation or lead to miscarriage.
  • Polyps: Uterine polyps are growths attached to the inner wall of the uterus that extend into the uterine cavity. They can reduce fertility and IVF success.
  • Abnormal Uterine Shape: Conditions like a bicornuate uterus (a heart-shaped uterus) can make it harder for an embryo to implant and grow.

It’s vital for women undergoing IVF to have a thorough uterine evaluation. This may include an ultrasound, hysteroscopy, or other diagnostic procedures to identify and treat any uterine abnormalities.

Depending on the issue, treatments may include medication, surgical intervention, or specific approaches during IVF to increase the chances of a successful pregnancy.

Body Mass Index (BMI)

BMI is a simple calculation using height and weight to categorize body fat. Here’s how it impacts IVF:

  • Underweight Challenges: Women with a BMI below 18.5 are considered underweight. This can lead to irregular menstrual cycles and ovulation issues, making it tough to conceive. It might also affect the quality of the eggs.
  • Overweight and Obesity: A BMI over 25 is considered overweight, and over 30 is obese. Higher BMI can be associated with decreased egg quality, reduced response to fertility drugs, and can also affect the health of the uterus, making implantation more difficult.
  • Hormonal Imbalances: Excess weight can lead to hormonal imbalances that can interfere with the reproductive process. For example, it can increase the risk of insulin resistance, which can affect ovulation.

Striving for a healthy BMI (18.5-24.9) can enhance IVF success rates. This often involves a balanced diet and regular exercise.

Lifestyle Factors

The way you live your life plays a big part in IVF success. Here’s why:

  • Smoking: It’s a big no-no. Smoking can reduce the quality of both eggs and sperm. It can also lead to fertility problems and decrease the success rate of IVF.
  • Alcohol and Drugs: Excessive alcohol and recreational drug use can harm egg and sperm quality. It’s best to limit alcohol and avoid drugs when trying for a baby through IVF.
  • Stress Factor: Stress can affect hormonal balance and overall health. It might not directly cause infertility, but it can make the journey tougher. Managing stress through relaxation techniques, exercise, or therapy can be beneficial.
  • Overall Healthy Living: Eating well, staying active, getting enough sleep, and avoiding harmful substances can boost your overall health and, in turn, improve the odds of IVF success.

When is an IVF Cycle Considered Successful?

An IVF cycle is deemed successful when it results in a pregnancy. About 14 days after the embryo transfer, doctors conduct a blood test known as Beta hCG. If this test is positive, it indicates a successful implantation and the start of a pregnancy.

Wrapping Up

IVF is a journey filled with hope and challenges. Understanding the factors influencing its success can help couples prepare better, both emotionally and physically. Remember, each couple’s journey is unique, and what works for one may not work for another. Consultation with fertility specialists is key to navigating this path effectively. With the right support and information, the dream of parenthood is within reach for many. If you need any further information about IVF’s success rate, feel free to talk to us. We will address all your concerns.

By Dr Samidha Dalvi-Amale

IVF and Fertility specialist Medical Director- Pune IVF

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