Assisted Laser Hatching (ALH) can significantly improve IVF outcomes in selected patients by enhancing embryo implantation. Success rates vary depending on factors such as maternal age, embryo quality, and medical history. On average, ALH can increase implantation rates by 10–20%, especially for women over 35, those with repeated IVF failures, or frozen embryos. While it does not guarantee pregnancy, when performed by skilled embryologists using advanced technology, ALH offers higher chances of achieving a successful pregnancy and fulfilling parenthood dreams.
Assisted Laser Hatching (ALH) is an advanced fertility technique used in conjunction with In-Vitro Fertilization (IVF). In natural conception, an embryo must break out of its outer shell, known as the zona pellucida, to successfully implant in the uterine lining. However, in some cases, the embryo’s outer shell is too thick or hard, making it difficult for implantation to occur. Assisted Laser Hatching helps overcome this barrier by creating a small opening in the zona pellucida using a highly precise laser beam.
This advanced procedure increases the chances of successful embryo implantation and pregnancy, especially in patients who have faced repeated IVF failures or have specific fertility concerns.
The procedure uses a precise laser to create a tiny opening in the embryo’s outer shell, helping it implant more easily.
After fertilization in the IVF lab, embryos are carefully monitored . Healthy embryos that reach the required stage of development are chosen for the procedure.
• The selected embryo is placed under a high-powered microscope equipped with a micromanipulator and laser system. • The embryologist examines the thickness and quality of the zona pellucida (the protective outer shell of the embryo).
• The embryo is gently held in place using a holding pipette to ensure stability. • The area where the opening will be created is carefully identified.
• A precise, computer-controlled laser beam is directed at a small area of the zona pellucida. • The laser creates a tiny hole or thins a part of the shell without touching or harming the embryo itself.
• The embryologist verifies that the opening is adequate to allow natural hatching later. • The embryo’s condition is carefully reassessed before proceeding.
• Once the assisted hatching is complete, the embryo is ready for transfer. • The embryo is then placed into the woman’s uterus, where it can implant successfully.
These steps in Assisted Laser Hatching, though advanced, provide a precise and reliable method to improve embryo implantation and support couples on their IVF journey to parenthood.
Not every IVF patient requires assisted hatching. It is generally recommended for:
Although Assisted Laser Hatching (ALH) is generally considered a safe and advanced fertility procedure, it carries some potential risks and complications. In rare cases, the laser may inadvertently damage the embryo, affecting its development. ALH does not guarantee improved implantation, especially if the underlying fertility issue is unrelated to embryo hatching. There is also a slightly increased chance of multiple pregnancies, which can pose higher risks for both mother and babies. Additionally, the procedure adds to the overall cost of IVF and requires highly skilled embryologists and advanced equipment to minimize risks. Despite these considerations, when performed at a reputable centre like Pune IVF, ALH is a precise, minimally invasive technique that can safely enhance the chances of successful embryo implantation.
Success Rates of ALH in IVF
Estimated Success Rates (when ALH is used with IVF)
The cost of Assisted Laser Hatching (ALH) in Pune varies based on factors such as the clinic’s reputation, the patient’s specific needs, and the inclusion of additional services. On average, the procedure ranges from ₹18,000 to ₹25,000.
Some clinics may offer ALH as part of a comprehensive IVF package, while others list it as an optional add-on. It’s essential to consult with your fertility specialist to understand the exact pricing and determine if ALH is suitable for your treatment plan.
Assisted Laser Hatching Cost Benefits at Pune IVF Fertility Centre, Pimple Saudagar