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Intrauterine Insemination (IUI)

Intrauterine Insemination (IUI) is a fertility treatment designed to help couples overcome certain types of infertility. It is one of the simplest and least invasive methods of assisted reproductive technology.

The process involves placing specially prepared sperms directly into a woman’s uterus during her ovulation period, increasing the chances of fertilization.

IUI can be particularly beneficial for couples dealing with unexplained infertility, mild male factor infertility, or cervical mucus problems, sexual dysfunction, couples separated by distance ( IUI with frozen sperms), sero discordant couples ( Male partners with HIV , Hepatitis B, etc)

With its relatively low cost and minimal side effects, IUI is often considered the first line of treatment before moving on to more complex procedures like in vitro fertilization (IVF).

This page provides comprehensive information on the IUI procedure, including its indications, preparation steps, potential risks, and success rates, helping you make an informed decision about your fertility journey.

IUI Process

The IUI process is straightforward and comprises several key steps, ensuring the procedure is performed during the optimal time in a woman’s menstrual cycle. Below is a detailed breakdown of the IUI process:

Ovarian Stimulation

In some cases, women may be given fertility medications to stimulate ovulation and increase the number of available eggs. This step is closely monitored through ultrasound and blood tests to track follicle development.


Regular visits to the clinic ensure that the growth of follicles and hormone levels are optimal for the procedure. Monitoring helps determine the precise time of ovulation, which is critical for the success of IUI.

Sperm Collection and Preparation

The male partner provides a sperm sample, either on the day of the IUI or in advance, which is then washed and concentrated. The washing process removes seminal fluid, dead sperm, and other impurities, leaving a healthy and motile sperm sample ready for insemination.


The IUI procedure is carefully timed to coincide with the woman's ovulation. Typically, ovulation occurs 36-48 hours post the administration of an ovulation-triggering injection, such as hCG (human chorionic gonadotropin).


A thin, flexible catheter is used to place the prepared sperm directly into the uterus. The procedure is quick, generally painless, and does not require anesthesia.


After the insemination, the patient is advised to lie down for a short period. Normal daily activities can be resumed soon after, but strenuous activities should be avoided.Usually a Progesterone supplement is given for 15 days post IUI to enhance the chances of conception.

Pregnancy Test

Around two weeks after the procedure, a blood test can be conducted to determine if the IUI was successful. Or else simply a urine pregnancy test can be taken in case the periods are missed for a week or so.

If pregnancy is not achieved, the process may be repeated in subsequent cycles or alternative treatments may be considered.

Understanding the IUI process can help alleviate concerns and set realistic expectations, making the journey toward parenthood more manageable and less stressful.

IUI Success Rate

The success rate of intrauterine insemination (IUI) varies based on multiple factors, including the woman’s age, the underlying cause of infertility, and the quality of the sperm sample.

On average, the success rate per IUI cycle ranges from 10% to 20%.

Younger women, particularly those under the age of 35, generally experience higher success rates as compared to older women. Additionally, the success of IUI can be influenced by certain conditions such as unexplained infertility, mild male factor infertility, and cervical mucus problems.

Understanding these variables can provide a more realistic perspective for couples considering IUI, helping them navigate their fertility journey with informed expectations.

multiple pregnancies

When to Prefer IUI?

Intrauterine insemination (IUI) can be a preferred fertility treatment option under certain circumstances. Couples facing unexplained infertility, where no specific cause has been identified despite extensive testing, might choose IUI as a first-line treatment due to its minimally invasive nature and relative affordability.

It is also a suitable choice for women who have issues with their cervical mucus, which might hinder sperm from reaching the egg.

Further, IUI is commonly recommended for couples dealing with mild male factor infertility, such as reduced sperm count or motility, as the process involves placing a concentrated sperm sample directly into the uterus, thus increasing the chances of fertilization.

Women with ovulatory disorders, such as polycystic ovary syndrome (PCOS), who do not ovulate regularly, might also benefit from IUI in conjunction with ovulation-stimulating medications.

Choosing IUI is often a guided decision made by fertility specialists based on individual health profiles, specific fertility issues, and overall treatment goals. Understanding when to prefer IUI can significantly optimize the chances of achieving a successful pregnancy.

Get the most advanced IUI treatment using world-class technology at the leading IUI Clinic in Pimple Saudagar, Pune. Consult with Dr. Samidha Dalvi today about your fertility-related concerns, available treatments, and IUI costs in Pimple Saudagar, Pune, India.

Advantages of IUI

There are several advantages to choosing intrauterine insemination (IUI) as a fertility treatment. Firstly, IUI is a relatively simple and less invasive procedure compared to other assisted reproductive technologies, such as in vitro fertilization (IVF). This makes it an attractive first-line treatment option.

Secondly, the process is generally cost-effective, which can be a significant consideration for many couples. Additionally, IUI requires minimal recovery time, allowing individuals to resume normal activities almost immediately post-procedure. The controlled timing of IUI also synchronizes sperm placement with ovulation, enhancing the chances of successful fertilization.

Risks Involved in IUI

While IUI can be an effective fertility treatment, it is important to be aware of the potential risks involved. One of the primary risks is the probability of multiple pregnancies (twins or triplets), especially when ovulation-stimulating medications are used. This can lead to complications such as premature birth and low birth weight.

Additionally, there is a small risk of infection as a result of the procedure. Finally, ovarian hyperstimulation syndrome (OHSS) is another potential risk associated with the use of fertility medications, which can cause ovaries to become swollen and painful. It is crucial for couples to discuss these risks with their fertility specialist to make an informed decision.

Limitations of IUI

Despite its advantages, intrauterine insemination (IUI) has certain limitations that couples should consider. One notable limitation is the lower success rate compared to more advanced treatments such as in vitro fertilization (IVF).

Success rates are influenced by factors such as age, underlying fertility issues, and the quality of sperm and eggs. Additionally, IUI may not be suitable for everyone; it is often less effective for individuals with severe male infertility factors, blocked fallopian tubes, or significant endometriosis.

Another limitation is the emotional toll; repeated IUI cycles without success can be stressful and emotionally draining for couples. Moreover, while the procedure is generally less expensive, the cumulative cost of multiple cycles can add up, making it a less viable option for some.

It is important for couples to have a thorough discussion with their fertility specialist to understand whether IUI is the appropriate treatment for their specific circumstances.

Cost of IUI at Pune IVF

The cost of intrauterine insemination (IUI) in Pune varies depending on the clinic and the specific services included in the treatment package.

 On an average, a single cycle of IUI at Pune IVF goes to INR 6,000.

This cost typically covers the procedure itself, semen preparation, media and consumables involved, initial consultations, and basic monitoring. However, additional expenses may arise for fertility medications, advanced diagnostic tests, and other ancillary services.

It is advisable for couples to obtain a detailed breakdown of costs from us to gain a comprehensive understanding of the financial commitment involved.

Couples should also consider potential travel and accommodation expenses if they are coming from outside Pune.

Please note- Pune IVF does not believe in giving multiple cycle IUI packages. We believe in quality work and strive hard to give you pregnancy in every single attempt even in IUI cycle

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